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the evolution of modern medicine(�峇�匳勞議處延)-及30嫗

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practice    was    followed     of  holding    a  professorial    discourse�察   �while    the 

butcher�察�or barber surgeon�察�opened the cavities of the body。 A member of a 

famous      Basel    family    of  physicians�察    �Felix   Plater�察 �has   left  us   in  his 

autobiography��19�А  �details   of   the   dissections   he   witnessed   at   Montpellier 

between      November       14�察 �1552�察   �and   January    10�察  �1557�察  �only    eleven   in 

number。 How difficult it was at that time to get subjects is shown by the 

risks they ran in ;body´snatching; expeditions�察�of which he records three。 

     ��19�А�There is no work from which we can get a better idea of the life of 



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the sixteenth´century medical student and of the style of education and of 

the degree ceremonies�察�etc。 Cumston has given an excellent summary of it 

��Johns Hopkins Hospital Bulletin�察�1912�察�XXIII�察�105´113��。 

       And now came the real maker of modern anatomy。 Andreas Vesalius 

had a good start in life。 Of a family long associated with the profession�察�

his   father   occupied   the   position   of   apothecary   to   Charles   V�察  �whom   he 

accompanied on his journeys and campaigns。 Trained at Louvain�察�he had�察�

from his earliest youth�察�an ardent desire   to dissect�察�and cut up mice   and 

rats�察�and even cats and dogs。 To Paris�察�the strong school of the period�察�he 

went in 1533�察�and studied under two men of great renown�察�Jacob Sylvius 

and Guinterius。 Both were strong Galenists and regarded the Master as an 

infallible   authority。   He   had   as   a   fellow   prosector�察  �under   the   latter�察  �the 

unfortunate Servetus。 The story of his troubles and trials in getting bones 

and     subjects    you    may    read    in  Roth's    ;Life。;��20�А    �Many      interesting 

biographical details are also to be found in his own writings。 He returned 

for a time to Louvain�察�and here he published his first book�察�a commentary 

on the ;Almansor; of Rhazes�察�in 1537。 

     ��20�А   �M。    Roth�此   �Andreas     Vesalius     Bruxellensis�察    �Berlin�察   �1892。    An 

excellent   account   of   Vesalius   and   his   contemporaries   is   given   by   James 

Moores   Ball   in   his   superbly   printed   Andreas   Vesalius�察  �the   Reformer   of 

Anatomy�察�St。 Louis�察�1910。 

     Finding it difficult�察�either in Paris or Louvain�察�to pursue his anatomical 

studies�察   �he   decided     to  go   to  Italy   where�察   �at  Venice    and    Padua�察   �the 

opportunities      were    greater。   At   Venice�察   �he   attended     the  practice    of  a 

hospital ��now a barracks�� which was in charge of the Theatiner Order。  I 

show you a photograph of the building taken last year。 And here a strange 

destiny brought two men together。 In 1537�察�another pilgrim was working 

in   Venice   waiting   to   be   joined   by   his   six   disciples。 After   long   years   of 

probation�察  �Ignatius   Loyola   was   ready   to   start   on   the   conquest   of   a   very 

different world。 Devoted to the sick and to the poor�察�he attached himself to 

the Theatiner Order�察�and in the wards of the hospital and the quadrangle�察�

the fiery�察�dark´eyed�察�little Basque must frequently have come into contact 

with   the   sturdy   young   Belgian�察  �busy   with   his   clinical   studies   and   his 

anatomy。   Both   were   to   achieve   phenomenal   successthe   one   in   a   few 



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years   to   revolutionize   anatomy�察  �the   other   within   twenty   years   to   be   the 

controller of universities�察�the counsellor of kings�察�and the founder of the 

most famous order in the Roman Catholic Church。 It was in this hospital 

that Vesalius made observations on the China´root�察�on which he published 

a   monograph       in  1546。    The   Paduan     School    was    close   to  Venice    and 

associated      with    it�察 �so  that   the   young     student    had    probably     many 

opportunities of going to and fro。 On the sixth of December�察�1537�察�before 

he had reached his twenty´fourth year and shortly after taking his degree�察�

he was elected to the chair of surgery and anatomy at Padua。 

     The   task Vesalius   set   himself   to   accomplish   was   to give   an   accurate 

description of all the parts of the human body�察�with proper illustrations。 He 

must have had abundant material�察�more�察�probably�察�than any teacher before 

him had ever had at his disposal。 We do not know where he conducted his 

dissections�察�as the old amphitheatre has disappeared�察�but it must have been 

very different from the tiny one put up by his successor�察�Fabricius�察�in 1594。 

Possibly   it   was   only   a   temporary   building�察  �for   he   says   in   the   second 

edition    of  the   ;Fabrica;    that   he  had   a  splendid    lecture   theatre   which 

accommodated more than five hundred spectators ��p。 681��。 

     With     Vesalius    disappeared      the   old   didactic    method     of   teaching 

anatomy。   He   did   his   own   dissections�察  �made   his   own   preparations�察  �and�察�

when     human     subjects    were    scarce�察  �employed      dogs�察  �pigs   or  cats�察 �and 

occasionally a monkey。 For five years he taught and worked at Padua。 He 

is known to have given public demonstrations in Bologna and elsewhere。 

In the ;China´root; he remarks that he once taught in three universities in 

one year。 The first fruit of his work is of great importance in connection 

with the evolution of his knowledge。 In 1538�察�he published six anatomical 

tables    issued    apparently     in   single   leaves。    Of   the   famous      ;Tabulae 

Anatomicae; only two copies are known�察�one in the San Marco Library�察�

Venice�察  �and   the   other   in   the   possession   of   Sir   John   Stirling´Maxwell�察�

whose father had it reproduced in facsimile ��thirty copies only�� in 1874。 

Some of the figures were drawn by Vesalius himself�察�and some are from 

the pencil of his friend and countryman�察�Stephan van Calcar。 Those plates 

were   extensively   pirated。   About   this   time   he   also   edited   for   the   Giunti 

some of the anatomical works of Galen。��21�А�



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     ��21    De    anatomicis     administrationibus�察      �De   venarum      arterinrumque 

dissectione�察�included in the various Juntine editions of Galen。 

       We know very little of his private life at Padua。 His most important 

colleague in the faculty was the famous Montanus�察�professor of medicine。 

Among his students and associates was the Englishman Caius�察�who lived 

in   the   same   house   with   him。   When   the   output   is   considered�察  �he   cannot 

have had much spare time at Padua。 

     He    did   not    create   human      anatomythat      had    been    done    by   the 

Alexandriansbut he studied it in so orderly and thorough a manner that 

for the first time in history it could be presented in a way that explained 

the entire structure of the human body。 Early in 1542 the MS。 was ready�察�

the drawings had been made with infinite care�察�the blocks for the figures 

had   been   cut�察  �and   in   September�察  �he   wrote   to   Oporinus   urging   that   the 

greatest   pains   should   be   taken   with   the   book�察  �that   the   paper   should   be 

strong and of equal thickness�察�the workmen chosen for their skill�察�and that 

every detail of the pictures must be distinctly visible。 He writes with the 

confidence   of   a   man   who   realized   the   significance   of   the   work   he   had 

done。 It is difficult to speak in terms of   moderation of the ;Fabrica。; To 

appreciate its relative value one must compare it with the other anatomical 

works of the period�察�and for this purpose I put before you two figures from 

a text´book on the subject that was available for students during the first 

half of the sixteenth century。 In the figures and text of the ;Fabrica; we 

have anatomy as we know it�察�and let us be honest and say�察�too�察�largely as 

Galen   knew   it。   Time   will   not   allow   me   to   go   into   the   question   of   the 

relations of these two great anatomists�察�but we must remember that at this 

period Galen ruled supreme�察�and was regarded in the schools as infallible。 

And   now�察  �after   five   years   of   incessant   labor�察  �Vesalius   was   prepared   to 

leave     his   much      loved    Padua     and    his   devoted      students。    He    had 

accomplished   an   extraordinary  work。   He   knew�察  �I   feel   sure�察  �what   he   had 

done。 He knew that the MSS。 contained something that the world had not 

seen     since   the   great   Pergamenian       sent   the   rolls  of   his   ;Manual     of 

Anatomy; among his friends。 Too precious to entrust to any printer but the 

bestand the best in the middle of the sixteenth century was Transalpine 

he was preparing to go north with the precious burden。 We can picture the 



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youthful teacherhe was but twenty´eightamong students in a university 

which   they   themselves   controlledsome   of   them   perhaps   the   very   men 

who five years before had elected himat the last meeting with his class�察�

perhaps giving a final demonstration of the woodcuts�察�which were of an 

accuracy and beauty never seen before by students' eyes�察�and reading his 

introduction。   There   would   be   sad   hearts   at   the   parting�察  �for   never   had 

anyone     taught    anatomy     as  he  had   taught   itno   one   had   ever   known 

anatomy as he knew it。 But the strong�察�confident look was on his face and 

with the courage of youth and sure of the future�察�he would picture a happy 

return   to   attack   new   and   untried   problems。   Little   did   he   dream   that   his 

happy   days   as   student   and   teacher   were   finished�察  �that   his   work   as   an 

anatomist was over�察�that the most brilliant and epoch´making part of his 

career as a professor was a thing of the past。 A year or more was spent at 

Basel with his friend Oporinus supervising the printing of the great work�察�

which appeared in 1543 with the title ;De Humani Corporis Fabrica。; The 

worth of a book�察�as of a man�察�must be judged by results�察�and�察�so judged�察�

the ;Fabrica; is one of the great books of the world�察�and would come in 

any century of volumes which embraced the richest harvest of the human 

mind。 In medicine�察�it represents the full flower of the Renaissance。 As a 

book it is a sumptuous tome a worthy setting of his jewelpaper�察�type and 

illustration to match�察�as you may see for yourselves i

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