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IV¡£¡¡ANATOMY¡¡AND¡¡PHYSIOLOGY¡¡IN¡¡THE¡¡EIGHTEENTH¡¡CENTURY
ALBRECHT¡¡VON¡¡HALLER
An¡¡epoch¡¡in¡¡physiology¡¡was¡¡made¡¡in¡¡the¡¡eighteenth¡¡century¡¡by¡¡the¡¡genius¡¡and¡¡efforts¡¡of¡¡Albrecht¡¡von¡¡Haller¡¡£¨1708¡1777£©£»¡¡of¡¡Berne£»¡¡who¡¡is¡¡perhaps¡¡as¡¡worthy¡¡of¡¡the¡¡title¡¡¡¨The¡¡Great¡¨¡¡as¡¡any¡¡philosopher¡¡who¡¡has¡¡been¡¡so¡¡christened¡¡by¡¡his¡¡contemporaries¡¡since¡¡the¡¡time¡¡of¡¡Hippocrates¡£¡¡¡¡Celebrated¡¡as¡¡a¡¡physician£»¡¡he¡¡was¡¡proficient¡¡in¡¡various¡¡fields£»¡¡being¡¡equally¡¡famed¡¡in¡¡his¡¡own¡¡time¡¡as¡¡poet£»¡¡botanist£»¡¡and¡¡statesman£»¡¡and¡¡dividing¡¡his¡¡attention¡¡between¡¡art¡¡and¡¡science¡£
As¡¡a¡¡child¡¡Haller¡¡was¡¡so¡¡sickly¡¡that¡¡he¡¡was¡¡unable¡¡to¡¡amuse¡¡himself¡¡with¡¡the¡¡sports¡¡and¡¡games¡¡common¡¡to¡¡boys¡¡of¡¡his¡¡age£»¡¡and¡¡so¡¡passed¡¡most¡¡of¡¡his¡¡time¡¡poring¡¡over¡¡books¡£¡¡¡¡When¡¡ten¡¡years¡¡of¡¡age¡¡he¡¡began¡¡writing¡¡poems¡¡in¡¡Latin¡¡and¡¡German£»¡¡and¡¡at¡¡fifteen¡¡entered¡¡the¡¡University¡¡of¡¡Tubingen¡£¡¡¡¡At¡¡seventeen¡¡he¡¡wrote¡¡learned¡¡articles¡¡in¡¡opposition¡¡to¡¡certain¡¡accepted¡¡doctrines£»¡¡and¡¡at¡¡nineteen¡¡he¡¡received¡¡his¡¡degree¡¡of¡¡doctor¡£¡¡Soon¡¡after¡¡this¡¡he¡¡visited¡¡England£»¡¡where¡¡his¡¡zeal¡¡in¡¡dissecting¡¡brought¡¡him¡¡under¡¡suspicion¡¡of¡¡grave¡robbery£»¡¡which¡¡suspicion¡¡made¡¡it¡¡expedient¡¡for¡¡him¡¡to¡¡return¡¡to¡¡the¡¡Continent¡£¡¡¡¡After¡¡studying¡¡botany¡¡in¡¡Basel¡¡for¡¡some¡¡time¡¡he¡¡made¡¡an¡¡extended¡¡botanical¡¡journey¡¡through¡¡Switzerland£»¡¡finally¡¡settling¡¡in¡¡his¡¡native¡¡city£»¡¡Berne£»¡¡as¡¡a¡¡practising¡¡physician¡£¡¡During¡¡this¡¡time¡¡he¡¡did¡¡not¡¡neglect¡¡either¡¡poetry¡¡or¡¡botany£»¡¡publishing¡¡anonymously¡¡a¡¡collection¡¡of¡¡poems¡£
In¡¡1736¡¡he¡¡was¡¡called¡¡to¡¡Gottingen¡¡as¡¡professor¡¡of¡¡anatomy£»¡¡surgery£»¡¡chemistry£»¡¡and¡¡botany¡£¡¡¡¡During¡¡his¡¡labors¡¡in¡¡the¡¡university¡¡he¡¡never¡¡neglected¡¡his¡¡literary¡¡work£»¡¡sometimes¡¡living¡¡and¡¡sleeping¡¡for¡¡days¡¡and¡¡nights¡¡together¡¡in¡¡his¡¡library£»¡¡eating¡¡his¡¡meals¡¡while¡¡delving¡¡in¡¡his¡¡books£»¡¡and¡¡sleeping¡¡only¡¡when¡¡actually¡¡compelled¡¡to¡¡do¡¡so¡¡by¡¡fatigue¡£¡¡During¡¡all¡¡this¡¡time¡¡he¡¡was¡¡in¡¡correspondence¡¡with¡¡savants¡¡from¡¡all¡¡over¡¡the¡¡world£»¡¡and¡¡it¡¡is¡¡said¡¡of¡¡him¡¡that¡¡he¡¡never¡¡left¡¡a¡¡letter¡¡of¡¡any¡¡kind¡¡unanswered¡£
Haller's¡¡greatest¡¡contribution¡¡to¡¡medical¡¡science¡¡was¡¡his¡¡famous¡¡doctrine¡¡of¡¡irritability£»¡¡which¡¡has¡¡given¡¡him¡¡the¡¡name¡¡of¡¡¡¨father¡¡of¡¡modern¡¡nervous¡¡physiology£»¡¨¡¡just¡¡as¡¡Harvey¡¡is¡¡called¡¡¡¨the¡¡father¡¡of¡¡the¡¡modern¡¡physiology¡¡of¡¡the¡¡blood¡£¡¨¡¡It¡¡has¡¡been¡¡said¡¡of¡¡this¡¡famous¡¡doctrine¡¡of¡¡irritability¡¡that¡¡¡¨it¡¡moved¡¡all¡¡the¡¡minds¡¡of¡¡the¡¡centuryand¡¡not¡¡in¡¡the¡¡departments¡¡of¡¡medicine¡¡alonein¡¡a¡¡way¡¡of¡¡which¡¡we¡¡of¡¡the¡¡present¡¡day¡¡have¡¡no¡¡satisfactory¡¡conception£»¡¡unless¡¡we¡¡compare¡¡it¡¡with¡¡our¡¡modern¡¡Darwinism¡£¡¨£§1£§
The¡¡principle¡¡of¡¡general¡¡irritability¡¡had¡¡been¡¡laid¡¡down¡¡by¡¡Francis¡¡Glisson¡¡£¨1597¡1677£©¡¡from¡¡deductive¡¡studies£»¡¡but¡¡Haller¡¡proved¡¡by¡¡experiments¡¡along¡¡the¡¡line¡¡of¡¡inductive¡¡methods¡¡that¡¡this¡¡irritability¡¡was¡¡not¡¡common¡¡to¡¡all¡¡¡¨fibre¡¡as¡¡well¡¡as¡¡to¡¡the¡¡fluids¡¡of¡¡the¡¡body£»¡¨¡¡but¡¡something¡¡entirely¡¡special£»¡¡and¡¡peculiar¡¡only¡¡to¡¡muscular¡¡substance¡£¡¡He¡¡distinguished¡¡between¡¡irritability¡¡of¡¡muscles¡¡and¡¡sensibility¡¡of¡¡nerves¡£¡¡In¡¡1747¡¡he¡¡gave¡¡as¡¡the¡¡three¡¡forces¡¡that¡¡produce¡¡muscular¡¡movements£º¡¡elasticity£»¡¡or¡¡¡¨dead¡¡nervous¡¡force¡¨£»¡¡irritability£»¡¡or¡¡¡¨innate¡¡nervous¡¡force¡¨£»¡¡and¡¡nervous¡¡force¡¡in¡¡itself¡£¡¡¡¡And¡¡in¡¡1752¡¡he¡¡described¡¡one¡¡hundred¡¡and¡¡ninety¡¡experiments¡¡for¡¡determining¡¡what¡¡parts¡¡of¡¡the¡¡body¡¡possess¡¡¡¨irritability¡¨that¡¡is£»¡¡the¡¡property¡¡of¡¡contracting¡¡when¡¡stimulated¡£¡¡His¡¡conclusion¡¡that¡¡this¡¡irritability¡¡exists¡¡in¡¡muscular¡¡substance¡¡alone¡¡and¡¡is¡¡quite¡¡independent¡¡of¡¡the¡¡nerves¡¡proceeding¡¡to¡¡it¡¡aroused¡¡a¡¡controversy¡¡that¡¡was¡¡never¡¡definitely¡¡settled¡¡until¡¡late¡¡in¡¡the¡¡nineteenth¡¡century£»¡¡when¡¡Haller's¡¡theory¡¡was¡¡found¡¡to¡¡be¡¡entirely¡¡correct¡£
It¡¡was¡¡in¡¡pursuit¡¡of¡¡experiments¡¡to¡¡establish¡¡his¡¡theory¡¡of¡¡irritability¡¡that¡¡Haller¡¡made¡¡his¡¡chief¡¡discoveries¡¡in¡¡embryology¡¡and¡¡development¡£¡¡He¡¡proved¡¡that¡¡in¡¡the¡¡process¡¡of¡¡incubation¡¡of¡¡the¡¡egg¡¡the¡¡first¡¡trace¡¡of¡¡the¡¡heart¡¡of¡¡the¡¡chick¡¡shows¡¡itself¡¡in¡¡the¡¡thirty¡eighth¡¡hour£»¡¡and¡¡that¡¡the¡¡first¡¡trace¡¡of¡¡red¡¡blood¡¡showed¡¡in¡¡the¡¡forty¡first¡¡hour¡£¡¡By¡¡his¡¡investigations¡¡upon¡¡the¡¡lower¡¡animals¡¡he¡¡attempted¡¡to¡¡confirm¡¡the¡¡theory¡¡that¡¡since¡¡the¡¡creation¡¡of¡¡genus¡¡every¡¡individual¡¡is¡¡derived¡¡from¡¡a¡¡preceding¡¡individualthe¡¡existing¡¡theory¡¡of¡¡preformation£»¡¡in¡¡which¡¡he¡¡believed£»¡¡and¡¡which¡¡taught¡¡that¡¡¡¨every¡¡individual¡¡is¡¡fully¡¡and¡¡completely¡¡preformed¡¡in¡¡the¡¡germ£»¡¡simply¡¡growing¡¡from¡¡microscopic¡¡to¡¡visible¡¡proportions£»¡¡without¡¡developing¡¡any¡¡new¡¡parts¡£¡¨
In¡¡physiology£»¡¡besides¡¡his¡¡studies¡¡of¡¡the¡¡nervous¡¡system£»¡¡Haller¡¡studied¡¡the¡¡mechanism¡¡of¡¡respiration£»¡¡refuting¡¡the¡¡teachings¡¡of¡¡Hamberger¡¡£¨1697¡1755£©£»¡¡who¡¡maintained¡¡that¡¡the¡¡lungs¡¡contract¡¡independently¡£¡¡Haller£»¡¡however£»¡¡in¡¡common¡¡with¡¡his¡¡contemporaries£»¡¡failed¡¡utterly¡¡to¡¡understand¡¡the¡¡true¡¡function¡¡of¡¡the¡¡lungs¡£¡¡¡¡The¡¡great¡¡physiologist's¡¡influence¡¡upon¡¡practical¡¡medicine£»¡¡while¡¡most¡¡profound£»¡¡was¡¡largely¡¡indirect¡£¡¡He¡¡was¡¡a¡¡theoretical¡¡rather¡¡than¡¡a¡¡practical¡¡physician£»¡¡yet¡¡he¡¡is¡¡credited¡¡with¡¡being¡¡the¡¡first¡¡physician¡¡to¡¡use¡¡the¡¡watch¡¡in¡¡counting¡¡the¡¡pulse¡£
BATTISTA¡¡MORGAGNI¡¡AND¡¡MORBID¡¡ANATOMY
A¡¡great¡¡contemporary¡¡of¡¡Haller¡¡was¡¡Giovanni¡¡Battista¡¡Morgagni¡¡£¨1682¡1771£©£»¡¡who¡¡pursued¡¡what¡¡Sydenham¡¡had¡¡neglected£»¡¡the¡¡investigation¡¡in¡¡anatomy£»¡¡thus¡¡supplying¡¡a¡¡necessary¡¡counterpart¡¡to¡¡the¡¡great¡¡Englishman's¡¡work¡£¡¡¡¡Morgagni's¡¡investigations¡¡were¡¡directed¡¡chiefly¡¡to¡¡the¡¡study¡¡of¡¡morbid¡¡anatomythe¡¡study¡¡of¡¡the¡¡structure¡¡of¡¡diseased¡¡tissue£»¡¡both¡¡during¡¡life¡¡and¡¡post¡¡mortem£»¡¡in¡¡contrast¡¡to¡¡the¡¡normal¡¡anatomical¡¡structures¡£¡¡This¡¡work¡¡cannot¡¡be¡¡said¡¡to¡¡have¡¡originated¡¡with¡¡him£»¡¡for¡¡as¡¡early¡¡as¡¡1679¡¡Bonnet¡¡had¡¡made¡¡similar£»¡¡although¡¡less¡¡extensive£»¡¡studies£»¡¡and¡¡later¡¡many¡¡investigators£»¡¡such¡¡as¡¡Lancisi¡¡and¡¡Haller£»¡¡had¡¡made¡¡post¡mortem¡¡studies¡£¡¡¡¡But¡¡Morgagni's¡¡De¡¡sedibus¡¡et¡¡causis¡¡morborum¡¡per¡¡anatomen¡¡indagatis¡¡was¡¡the¡¡largest£»¡¡most¡¡accurate£»¡¡and¡¡best¡illustrated¡¡collection¡¡of¡¡cases¡¡that¡¡had¡¡ever¡¡been¡¡brought¡¡together£»¡¡and¡¡marks¡¡an¡¡epoch¡¡in¡¡medical¡¡science¡£¡¡From¡¡the¡¡time¡¡of¡¡the¡¡publication¡¡of¡¡Morgagni's¡¡researches£»¡¡morbid¡¡anatomy¡¡became¡¡a¡¡recognized¡¡branch¡¡of¡¡the¡¡medical¡¡science£»¡¡and¡¡the¡¡effect¡¡of¡¡the¡¡impetus¡¡thus¡¡given¡¡it¡¡has¡¡been¡¡steadily¡¡increasing¡¡since¡¡that¡¡time¡£
WILLIAM¡¡HUNTER
William¡¡Hunter¡¡£¨1718¡1783£©¡¡must¡¡always¡¡be¡¡remembered¡¡as¡¡one¡¡of¡¡the¡¡greatest¡¡physicians¡¡and¡¡anatomists¡¡of¡¡the¡¡eighteenth¡¡century£»¡¡and¡¡particularly¡¡as¡¡the¡¡first¡¡great¡¡teacher¡¡of¡¡anatomy¡¡in¡¡England£»¡¡but¡¡his¡¡fame¡¡has¡¡been¡¡somewhat¡¡overshadowed¡¡by¡¡that¡¡of¡¡his¡¡younger¡¡brother¡¡John¡£
Hunter¡¡had¡¡been¡¡intended¡¡and¡¡educated¡¡for¡¡the¡¡Church£»¡¡but¡¡on¡¡the¡¡advice¡¡of¡¡the¡¡surgeon¡¡William¡¡Cullen¡¡he¡¡turned¡¡his¡¡attention¡¡to¡¡the¡¡study¡¡of¡¡medicine¡£¡¡His¡¡first¡¡attempt¡¡at¡¡teaching¡¡was¡¡in¡¡1746£»¡¡when¡¡he¡¡delivered¡¡a¡¡series¡¡of¡¡lectures¡¡on¡¡surgery¡¡for¡¡the¡¡Society¡¡of¡¡Naval¡¡Practitioners¡£¡¡¡¡These¡¡lectures¡¡proved¡¡so¡¡interesting¡¡and¡¡instructive¡¡that¡¡he¡¡was¡¡at¡¡once¡¡invited¡¡to¡¡give¡¡others£»¡¡and¡¡his¡¡reputation¡¡as¡¡a¡¡lecturer¡¡was¡¡soon¡¡established¡£¡¡He¡¡was¡¡a¡¡natural¡¡orator¡¡and¡¡story¡teller£»¡¡and¡¡he¡¡combined¡¡with¡¡these¡¡attractive¡¡qualities¡¡that¡¡of¡¡thoroughness¡¡and¡¡clearness¡¡in¡¡demonstrations£»¡¡and¡¡although¡¡his¡¡lectures¡¡were¡¡two¡¡hours¡¡long¡¡he¡¡made¡¡them¡¡so¡¡full¡¡of¡¡interest¡¡that¡¡his¡¡pupils¡¡seldom¡¡tired¡¡of¡¡listening¡£¡¡¡¡He¡¡believed¡¡that¡¡he¡¡could¡¡do¡¡greater¡¡good¡¡to¡¡the¡¡world¡¡by¡¡¡¨publicly¡¡teaching¡¡his¡¡art¡¡than¡¡by¡¡practising¡¡it£»¡¨¡¡and¡¡even¡¡during¡¡the¡¡last¡¡few¡¡days¡¡of¡¡his¡¡life£»¡¡when¡¡he¡¡was¡¡so¡¡weak¡¡that¡¡his¡¡friends¡¡remonstrated¡¡against¡¡it£»¡¡he¡¡continued¡¡his¡¡teaching£»¡¡fainting¡¡from¡¡exhaustion¡¡at¡¡the¡¡end¡¡of¡¡his¡¡last¡¡lecture£»¡¡which¡¡preceded¡¡his¡¡death¡¡by¡¡only¡¡a¡¡few¡¡days¡£
For¡¡many¡¡years¡¡it¡¡was¡¡Hunter's¡¡ambition¡¡to¡¡establish¡¡a¡¡museum¡¡where¡¡the¡¡study¡¡of¡¡anatomy£»¡¡surgery£»¡¡and¡¡medicine¡¡might¡¡be¡¡advanced£»¡¡and¡¡in¡¡1765¡¡he¡¡asked¡¡for¡¡a¡¡grant¡¡of¡¡a¡¡plot¡¡of¡¡ground¡¡for¡¡this¡¡purpose£»¡¡offering¡¡to¡¡spend¡¡seven¡¡thousand¡¡pounds¡¡on¡¡its£»¡¡erection¡¡besides¡¡endowing¡¡it¡¡with¡¡a¡¡professorship¡¡of¡¡anatomy¡£¡¡Not¡¡being¡¡able¡¡to¡¡obtain¡¡this¡¡grant£»¡¡however£»¡¡he¡¡built¡¡a¡¡house£»¡¡in¡¡which¡¡were¡¡lecture¡¡and¡¡dissecting¡¡rooms£»¡¡and¡¡his¡¡museum¡£¡¡In¡¡this¡¡museum¡¡were¡¡anatomical¡¡preparations£»¡¡coins£»¡¡minerals£»¡¡and¡¡natural¡history¡¡specimens¡£
Hunter's¡¡weakness¡¡was¡¡his¡¡love¡¡of¡¡controversy¡¡and¡¡his¡¡resentment¡¡of¡¡contradiction¡£¡¡¡¡This¡¡brought¡¡him¡¡into¡¡strained¡¡relations¡¡with¡¡many¡¡of¡¡the¡¡leading¡¡physicians¡¡of¡¡his¡¡time£»¡¡notably¡¡his¡¡own¡¡brother¡¡John£»¡¡who¡¡himself¡¡was¡¡probably¡¡not¡¡entirely¡¡free¡¡from¡¡blame¡¡in¡¡the¡¡matter¡£¡¡Hunter¡¡is¡¡said¡¡to¡¡have¡¡excused¡¡his¡¡own¡¡irritability¡¡on¡¡the¡¡grounds¡¡that¡¡being¡¡an¡¡anatomist£»¡¡and¡¡accustomed¡¡to¡¡¡¨the¡¡passive¡¡submission¡¡of¡¡dead¡¡bodies£»¡¨¡¡contradictions¡¡became¡¡the¡¡more¡¡unbearable¡£¡¡Many¡¡of¡¡the¡¡physiological¡¡researches¡¡begun¡¡by¡¡him¡¡were¡¡carried¡¡on¡¡and¡¡perfected¡¡by¡¡his¡¡more¡¡famous¡¡brother£»¡¡particularly¡¡his¡¡investigations¡¡of¡¡the¡¡capillaries£»¡¡but¡¡he¡¡added¡¡much¡¡to¡¡the¡¡anatomical¡¡knowledge¡¡of¡¡several¡¡structures¡¡of¡¡the¡¡body£»¡¡notably¡¡as¡¡to¡¡the¡¡structure¡¡of¡¡cartilages¡¡and¡¡joints¡£
JOHN¡¡HUNTER
In¡¡Abbot¡¡Islip's¡¡chapel¡¡in¡¡Westminster¡¡Abbey£»¡¡close¡¡to¡¡the¡¡resting¡place¡¡of¡¡Ben¡¡Jonson£»¡¡rest¡¡the¡¡remains¡¡of¡¡John¡¡Hunter¡¡£¨1728¡1793£©£»¡¡famous¡¡in¡¡the¡¡annals¡¡of¡¡medicine¡¡as¡¡among¡¡the¡¡greatest¡¡physiologists¡¡and¡¡surgeons¡¡that¡¡the¡¡world¡¡has¡¡ever¡¡produced£º¡¡a¡¡man¡¡whose¡¡discoveries¡¡and¡¡inventions¡¡are¡¡counted¡¡by¡¡scores£»¡¡and¡¡whose¡¡field¡¡of¡¡research¡¡was¡¡only¡¡limited¡¡by¡¡the¡¡outermost¡¡boundaries¡¡of¡¡eighteenth¡century¡¡science£»¡¡although¡¡his¡¡efforts¡¡were¡¡directed¡¡chiefly¡¡along¡¡the¡¡lines¡¡of¡¡his¡¡profession¡£
Until¡¡about¡¡twenty¡¡years¡¡of¡¡age¡¡young¡¡Hunter¡¡had¡¡shown¡¡little¡¡aptitude¡¡for¡¡study£»¡¡being¡¡unusually¡¡fond¡¡of¡¡out¡door¡¡sports¡¡and¡¡amusements£»¡¡but¡¡about¡¡that¡¡time£»¡¡realizing¡¡that¡¡some¡¡occupation¡¡must¡¡be¡¡selected£»¡¡he¡¡asked¡¡permission¡¡of¡¡his¡¡brother¡¡William¡¡to¡¡attempt¡¡some¡¡dissections¡¡in¡¡his¡¡anatomical¡¡school¡¡in¡¡London¡£¡¡¡¡To¡¡the¡¡surprise¡¡of¡¡his¡¡brother¡¡he¡¡made¡¡this¡¡dissection¡¡unusually¡¡well£»¡¡and¡¡being¡¡given¡¡a¡¡second£»¡¡he¡¡acquitted¡¡himself¡¡with¡¡such¡¡skill¡¡that¡¡his¡¡brother¡¡at¡¡once¡¡predicted¡¡that¡¡he¡¡would¡¡become¡¡a¡¡great¡¡anatomist¡£¡¡¡¡Up¡¡to¡¡this¡¡time¡¡he¡¡had¡¡had¡¡no¡¡training¡¡of¡¡any¡¡kind¡¡to¡¡prepare¡¡him¡¡for¡¡his¡¡professional¡¡career£»¡¡and¡¡knew¡¡little¡¡of